Central to the wellbeing of any living organism is the nucleus of the cell. It stores and organises genetic information and protects this information from other cellular components. The nucleus also communicates with the rest of the cell, exchanges proteins and RNA, and facilitates several important...

Platinum chemotherapeutics are used especially in patients with highly metastatic triple-negative breast cancers (TNBC). The chemotherapy is non-selective and toxic causing negative side effects that have been well documented. TNBC also readily acquires resistance to platinum-based therapies...

Triple-Negative Breast Cancer (TNBC) is a particularly aggressive cancer which mostly affects women of colour who are younger than 50 years of age. It is named for the fact that it tests negative for two hormone receptors and an excess of a certain protein; the typical indicators of breast cancer...

This invention pertains to a method for chemically synthesising novel classes of silver complexes that target specific forms of cancer with demonstrable anticancer activity in cell culture (in vitro). Most noteworthy is thus far, these complexes have better preliminary results than standard...

Wits researchers have developed a compound for the treatment of age-related diseases, such as cancer and cellular ageing. The compound occurs naturally in the body, and reduces the effects of telomerase activity in cells in a manner that prevents ageing of the cells. The compound, a protein fragment...