Central to the wellbeing of any living organism is the nucleus of the cell. It stores and organises genetic information and protects this information from other cellular components. The nucleus also communicates with the rest of the cell, exchanges proteins and RNA, and facilitates several important...

Platinum chemotherapeutics are used especially in patients with highly metastatic triple-negative breast cancers (TNBC). The chemotherapy is non-selective and toxic causing negative side effects that have been well documented. TNBC also readily acquires resistance to platinum-based therapies...

A Disintegrin and Metalloproteinase (ADAM10) is a cell-surface-expressed metalloproteinase. It is a type of protein enzyme with a catalytic mechanism involving a metal. Playing a role in various processes including cell adhesion (cells interacting and attaching to neighbouring cells), proliferation...