Innovations

Background Various cancers, including gynecological cancers, are becoming resistant or insensitive to platinum-based chemotherapy and consequently higher dosages are required to be effective. Unfortunately, most of these chemotherapeutic drugs cause undesirable systemic effects such as cardiac or

This technology relates to the transdermal treatment of diabetes. In particular, to a formulation for the transdermal delivery of the photoactive antidiabetic agent diosgenin that is encapsulated and protected by an oil-in-water nanoemulsion matrix for the treatment of type 11 diabetes Mellitus

The innovation is the rational combination of ezetimibe and curcumin for the treatment of colon cancer- which means one can apply a cancer therapeutic, orally. This would have significant value to the African population and solve key issues like the packaging and distribution of chemotherapeutic

Background Immortalized cell lines have been used extensively in cancer biology and as a model system to test the efficacy of vaccines, but their use is becoming increasingly limited because of extensive genetic and phenotypic variations compared to those expressed in cancer patients. Similarly

Surfactants are amphipathic molecules with both hydrophilic and hydrophobic moieties that partition preferentially at the interface between fluid phases such as oil/water or air/water interfaces. Such characteristics confer excellent detergency, emulsifying, foaming, and dispersing traits, which

The collection and preservation of biological material for further DNA and RNA analysis are critical to many biomedical fields, from medical diagnostics to forensics and biodiversity conservation. The Forensic DNA lab at the University of the Western Cape has developed a novel, proprietary DNA

Baobab LIMS is an African-led innovation that was developed as part of the B3Africa consortium. It is an affordable sample and laboratory management tool for biobanking that has been implemented in low- and middle-income countries (LMICs), which previously (due in part to financial constraints)

South Africa harbours the highest number of rape incidents in the world, and sexual assault and rape cases in the entire SADC region are estimated at a minimum of 55 000 cases per year. Crime scene investigations utilise DNA technology on a regular basis. In cases of rape or sexual abuse, male