Platinum chemotherapeutics are used especially in patients with highly metastatic triple-negative breast cancers (TNBC). The chemotherapy is non-selective and toxic causing negative side effects that have been well documented. TNBC also readily acquires resistance to platinum-based therapies...

A Disintegrin and Metalloproteinase (ADAM10) is a cell-surface-expressed metalloproteinase. It is a type of protein enzyme with a catalytic mechanism involving a metal. Playing a role in various processes including cell adhesion (cells interacting and attaching to neighbouring cells), proliferation...

Parkinson’s disease (PD) is the most frequent neurodegenerative disease of motor activity, with more than 10 million people worldwide suffering from the disease. One of the major causes of PD is a shortage of dopamine, which is important to motor functioning in the body. Additionally, in PD, a...

Atherosclerosis is a chronic, progressive disease which involves the blockage of the arteries, and is the major form of cardiovascular disease (CVD). It is often comorbid with obesity, insulin resistance and/or diabetes. This disease is the result of the formation of atherosclerotic plaques which...

Tungsten carbides coatings are used in drills and cutting tools to provide a desirable operational lifetime of the coatings in use, as they have enhanced mechanical and wear properties. They are typically deposited using thermal spraying techniques. Tungsten carbides deposited using these techniques...

This invention pertains to a method for chemically synthesising novel classes of silver complexes that target specific forms of cancer with demonstrable anticancer activity in cell culture (in vitro). Most noteworthy is thus far, these complexes have better preliminary results than standard...

Wits researchers have developed a water treatment plant which removes organic pollutants from municipal bulk water. The process is environmentally friendly, making use of sunlight to purify water, thus saving energy and eliminating the need to use chemicals. Its modular design allows for scaling...

The novel solar trough plant receiver is customizable based on the solar field needs, providing improvements in the harnessing of solar energy. Unlike conventional parabolic trough solar systems, it has a wider operational temperature range as well as high-efficiency levels which not only reduce...

Avril Biopharma’s main focus is rapid development of diagnostic, vaccine and therapeutic products using bioinformatics to design these products and our AdCEV(TM) protein expression technology to produce them inexpensively in hen eggs.
We are using our platform to address the urgent public-health demand for COVID-19 diagnostic testing and safe vaccine production. We are developing simple point-of-care test-kit products including a 5-10 minute saliva test for SARS-CoV-2 infection using components we can make in hen eggs. With our high yields, enough material for thousands of individual tests

COVID-19 disease cause pulmonary infections, which could be observed by CT images of the lungs as well as chest X-ray images. Clinicians have been able to observe and diagnose similar infection such pneumonia using this approach. In fact asymptomatic breast cancer and diabetes testing can currently be done using AI image processing.

A anonymised dataset of chest x ray images of Covid-19 infected patients as well as healthy patients is sampled. A convolutional neural network model is trained to analyse chest x -ray images, detect and label COVID-19 infected cases. Mobile chest X ray