Investigation of the synergistic impact of Artemisia afra and Cannabis sativa against SARS-CoV-2 and PIMS, and the removal of Δ9-THC using molecular imprinted polymers (MIPS).

COVID-19 pandemic has negatively impacted global economies and societal systems with over 4 million confirmed cases and 285, 000 deaths as of May 15, 2020 (WHO, 2020). Despite the ever-increasing cases and the likelihood of a future outbreak, there is currently no known treatment of SARS-CoV-2. The…

A COVID-19 detection home kit

The research involves developing a simple home detection kit for COVID-19. The first stage of the project involves the identification of proteins from bacteria that has a binding affinity to specific sites on the SARS-CoV2 S protein. Computational analysis will investigate the binding potential of…

Clinical effectiveness of lopinavir in the management of Covid-19 infection and prevention.

COVID-19 also known as Coronavirus 2019, is currently declared by WHO as a new pandemic
disease caused by a single-stranded RNA zoonotic virus termed severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) (Lu et al. 2020). The complete viral genome analysis shows that the…

Design and testing of novel viral fusion inhibitors against SARS-CoV-2

This project has employed computational (in silico) methods to design a novel class of inhibitors against the SARS-CoV-2 virus (COVID-19). The project has employed state-of-the-art computer-aided drug design (CADD) methods to develop an initial library of putative small molecule inhibitors. Because…